Isolation and characterization of an N-acetylgalactosamine specific lectin from Salvia sclarea seeds.

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Isolation and characterization of an N-acetylgalactosamine specific lectin from Salvia sclarea seeds.

Crude extracts from Salvia sclarea seeds were known to contain a lectin which specifically agglutinates Tn erythrocytes (Bird, G. W. G., and Wingham, G. (1974) Vox Sang. 26, 163-166). We have purified the lectin to homogeneity by ion-exchange chromatography and affinity chromatography. The agglutinin was found to be a glycoprotein of Mr = 50,000, composed of two identical subunits of Mr = 35,00...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1986

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)66982-0